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Vitamin B12 Injections

The Importance of B12

Vitamin B12 plays a key role in many body systems and organs and this list is increasing. It is needed for energy production through the Krebs Cycle, for the synthesis of DNA via the folate cycle which affects trillions of cells in the body, and for the expression of genes through epigenetic processes. It affects the proper functioning of the nervous and peripheral systems, mood and cognitive functions and the formation of blood in the bone marrow, skin and mucous membranes, bones, the glandular system, the immune system, the digestive system, fertility and pregnancy and development of the embryo.
Vitamin B12 deficiency consequently manifests as a wide range of different symptoms, some of which appear to be unrelated or may even be misdiagnosed. B12 is fundamental to animal life and metabolism that the symptoms are also widespread.

B12 is responsible for:
● Manufacture and normal function of blood cells.
● It rapidly divides all cells from epithelial cells to bone marrow cells.
● Energy production through the Krebs Cycle.
● Metabolism of fats, carbohydrates and proteins.
● Nerve cell conduction.
● Neurotransmitters.
● Endocrine systems.
● Immune systems.
● Conversion of homocysteine to methionine, then to SAMe (mood enhancing) and amino acids,
with effects on many metabolic processes.
● Correct synthesis and transcription of DNA.
● Removal of toxins.

While B-12 supplements and foods fortified with the vitamin are readily available, vitamin B-12 shots are only available by prescription, so a clinical diagnosis is always necessary. It is important to note that low levels are rare in most healthy adults because the human liver stores several years’ worth of vitamin B-12. However, some groups of people are more at risk of deficiency than others and may wish to discuss the possibility of B12 shots with their doctor. These at-risk groups include:

People with signs and symptoms of B12 deficiency.
Anyone who is displaying any of the signs and symptoms of a B12 deficiency or pernicious anemia should consult their doctor immediately.
Some common signs and symptoms include:
● decreased cognitive function, such as issues with memory or understanding
● fatigue
● lethargy
● constipation
● feeling faint
● depression or irritability
● headache
● difficulty maintaining balance
● sore, swollen tongue, which may be pale yellow or very red
● heart palpitations
● mouth ulcers
● paraesthesia (pins and needles)
● vision changes

The traditional way of diagnosing vitamin B12 deficiency has been with a serum B12 blood test to determine the patients B12 levels as well as the presence of any signs or symptoms of pernicious anaemia. The problem with this is that many sufferers of a B12 deficiency may not have anaemia or have a serum B12 blood level within an abnormally low range in accordance to the ‘normal’ ranges set. There are no national or international agreements of what a normal range is. The tests can also give false readings where they do not assess the bioavailability of the B12 or whether it is functional or not.
It is therefore better practice to look for trigger symptoms and undertake a one-minute health check to see if a client will benefit from B12 injections.
Key triggers or symptoms of vitamin B12 deficiency are:
● Tiredness
● Depression
● Hair loss
● Pins & needles
● Numbness in the hands or feet
● Tremors or palsies
● Palpitations
● Recurrent headaches
● Dizziness

Experience has shown that vitamin B12 is completely safe, at any concentration in the diet and in the blood. The non-toxicity of Vitamin B12 is confirmed by the US National Institute of Health Office of Dietary Supplements which states that the US Institute of Medicine (IoM) has not established any upper limit for B12 ‘because of its low toxicity’. The IoM states that ‘no adverse effects have been associated with excess vitamin B12 intake from food and supplements in healthy individuals’. The European Food Safety Authority (EFSA) states that the European Committee on Food (SCF) has concluded that ‘it is not possible to derive an upper intake level, mainly because no clearly identified adverse effect could be identified’.


Standard treatment is to give a loading dose of intramuscular injections of 1mg per 1ml ampoule of hydroxocobalamin every other week for 4 weeks, then inject once every three to four weeks.
Vitamin B12 injections are a nutritional supplement and not a medicine. With proper use of sterile technique there should be minimal to no risk. It is usual to inject into the muscle (intramuscular -IM).
This is because B12 is water-soluble and flows into the fluids. Surrounding the cells of the muscle. It is therefore easily transferred into the bloodstream from an IM injection.
Injection into the subcutaneous layer is not effective like it is with fat-soluble vitamins. Injecting into the subcutaneous layer can leave a red mark on the skin, which may be due to the red colour of the vitamin B12 being trapped in the fatty tissue.

Most clients will see results immediately after their first treatment, and the best results will be after 3 days of having the treatment, but we do highly recommend having at least 6 treatments to maximise results and get the longevity out of the procedure.
Vitamin B12 Injections
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